Metenolone is a long-acting anabolic steroid with weak androgenic (testosterone or androsterone-like) properties. This substance was added to the doping list ahead of the Los Angeles 1984 Olympic Games. This new method of detecting the drug is the reason for the high number of banned athletes since 2012 and onward.
This compound was first included in the WADA Prohibited List in 2004 as part of steroid profiling. This isomer of 5α-reduced androstane was referenced in WADA documentation from 2004 in the context of metabolite profiling for steroid abuse. This steroid metabolite was first identified in WADA documentation from 2004 for its role in androgen profiling. Stimulants directly affect the central nervous system, increasing blood flow and heart rate. Masking agents, on the other hand, work by making drug tests ineffective, leading to false-negative results. Metabolic modulators including peroxisome proliferator-activated receptor delta (PPARδ) agonists (e.g., GW 1516), PPARδ-AMP-activated protein kinase (AMPK) axis agonists (e.g. AICAR) are also banned. Selective estrogen receptor modulators, including raloxifene, tamoxifen and toremifene are banned.
The relevant medical authority must be informed of their use prior to competition. The substance is permitted by use of inhalers only to prevent and/or treat asthma and exercise induced asthma. This beta-2 agonist was first listed in the WADA Prohibited List from 2004 with dosage thresholds and inhalation limitations. It relieves inflammation (swelling, heat, redness, and pain) and is used to treat certain forms of arthritis; skin, blood, kidney, eye, thyroid, and intestinal disorders (e.g., colitis); severe allergies; and asthma. It is often used to replace this chemical when your body does not make enough of it. Methylprednisolone, a corticosteroid, is similar to a natural hormone produced by your adrenal glands.
Modern detection methods and hematocrit monitoring have made EPO use more detectable, though related substances and microdosing practices continue to challenge anti-doping authorities. EPO was added to the IOC prohibited list in 1989, initially categorized under peptide hormones and analogues. Oxandrolone is also used to treat bone pain in people with osteoporosis and to prevent certain side effects in people who take corticosteroids for a long time.
This class was first addressed by WADA in 2005 due to its influence on steroid metabolism. This substance was first mentioned in the WADA Prohibited List in 2004 in the context of plasma expansion. It is used in people with certain types of glaucoma to reduce the amount of fluid in the eye, which decreases pressure inside the eye.Acetazolamide is also used as a diuretic ("water pill") in people with congestive heart failure, to reduce the build-up of fluid in the body. Blocking this protein can help reduce the build-up of certain fluids in the body. Acetazolamide is used in the treatment of glaucoma, drug-induced edema, heart failure-induced edema, epilepsy and in reducing intraocular pressure after surgery. In women who do not produce ova (eggs) but wishes to become pregnant, clomiphene is used to induce ovulation (egg production).The substance is also sometimes used to treat male infertility.